Anemarsaponin BII inhibits the activity of CYP3A4, 2D6, and 2E1 with human liver microsomes

• المؤلفون الرئيسيون: Mingwei Wang (مؤلف), Wei Jiang (مؤلف), Juan Zhou (مؤلف), Xiujuan Xue (مؤلف), Changlong Yin (مؤلف)
• التنسيق: كتاب
• منشور في: Taylor & Francis Group, 2020-01-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

Context Anemarsaponin BII is one of the most active saponins isolated from Anemarrhena asphodeloides Bunge (Asparagaceae), a commonly used Chinese traditional paediatric medicine. Objective This study investigates the effects of anemarsaponin BII on the activity of CYP450s to provide more guidance f...