Limited Effects of Type I Interferons on Kyasanur Forest Disease Virus in Cell Culture.

• Main Authors: Bradley W M Cook (Author), Charlene Ranadheera (Author), Aidan M Nikiforuk (Author), Todd A Cutts (Author), Darwyn Kobasa (Author), Deborah A Court (Author), Steven S Theriault (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2016-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND:The tick-borne flavivirus, Kyasanur Forest disease virus (KFDV) causes seasonal infections and periodic outbreaks in south-west India. The current vaccine offers poor protection with reported issues of coverage and immunogenicity. Since there are no approved prophylactic therapeutics for...