Circulating fibroblast growth factor-2 precipitates HIV nephropathy in mice

• Main Authors: Jharna R. Das (Author), Marina Jerebtsova (Author), Pingtao Tang (Author), Jinliang Li (Author), Jing Yu (Author), Patricio E. Ray (Author)
• Format: Book
• Published: The Company of Biologists, 2021-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

People of African ancestry living with the human immunodeficiency virus-1 (HIV-1) are at risk of developing HIV-associated nephropathy (HIVAN). Children with HIVAN frequently show high plasma fibroblast growth factor-2 (FGF-2) levels; however, the role of circulating FGF-2 in the pathogenesis of chi...