Infant with diffuse large B-cell lymphoma identified postmortem with homozygous founder Slavic RAG1 variant: a case report and literature review

• Main Authors: Tatiana P. Volodashchik (Author), Ekaterina A. Polyakova (Author), Taisia M. Mikhaleuskaya (Author), Inga S. Sakovich (Author), Aleksandra N. Kupchinskaya (Author), Aliaxandr Ch. Dubrouski (Author), Mikhail V. Belevtsev (Author), Joseph F. Dasso (Author), Dzmitry S. Varabyou (Author), Luigi D. Notarangelo (Author), Jolan E. Walter (Author), Svetlana O. Sharapova (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background and aimsThere is an increased risk of lymphomas in inborn errors of immunity (IEI); however, germline genetic testing is rarely used in oncological patients, even in those with early onset of cancer. Our study focuses on a child with a recombination-activating gene 1 (RAG1) deficiency who...