Adipose tissue-specific ablation of PGC-1β impairs thermogenesis in brown fat

• Main Authors: Jiří Funda (Author), Josep A. Villena (Author), Kristina Bardova (Author), Katerina Adamcova (Author), Illaria Irodenko (Author), Pavel Flachs (Author), Ivana Jedlickova (Author), Eliska Haasova (Author), Martin Rossmeisl (Author), Jan Kopecky (Author), Petra Janovska (Author)
• Format: Book
• Published: The Company of Biologists, 2022-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Impaired thermogenesis observed in mice with whole-body ablation of peroxisome proliferator-activated receptor-γ coactivator-1β (PGC-1β; officially known as PPARGC1B) may result from impaired brown fat (brown adipose tissue; BAT) function, but other mechanism(s) could be involved. Here, using adipos...