Design, synthesis and anticancer activity of naphthoquinone derivatives

• Asıl Yazarlar: Xiao-bao Shen (Yazar), Yang Wang (Yazar), Xuan-zhen Han (Yazar), Liang-quan Sheng (Yazar), Fu-fang Wu (Yazar), Xinhua Liu (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Taylor & Francis Group, 2020-01-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Basis on molecular docking and pharmacophore analysis of naphthoquinone moiety, a total of 23 compounds were designed and synthesised. With the help of reverse targets searching, anti-cancer activity was preliminarily evaluated, most of them are effective against some tumour cells, especially compou...