Expression of n-MYC, NAMPT and SIRT1 in Basal Cell Carcinomas and their Cells of Origin
Deregulated Hedgehog signalling is a driver of basal cell carcinomas. One effector of the Hedgehog pathway is n-MYC. c/n-MYC proteins, NAMPT and DBC1 are linked to SIRT1 in a positive feedback loop that may contribute to tumorigenesis of basal cell carcinoma. In 5 basal cell carcinoma types immunohi...
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Format: | Book |
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Medical Journals Sweden,
2018-09-01T00:00:00Z.
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A1234.567 |
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