Review immune response of targeting CD39 in cancer

• Main Authors: Yao Liu (Author), Zhongliang Li (Author), Xiaoguang Zhao (Author), Jing Xiao (Author), Jiacheng Bi (Author), Xian-Yang Li (Author), Guokai Chen (Author), Ligong Lu (Author)
• Format: Book
• Published: BMC, 2023-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract The ATP-adenosine pathway has emerged as a promising target for cancer therapy, but challenges remain in achieving effective tumor control. Early research focused on blocking the adenosine generating enzyme CD73 and the adenosine receptors A2AR or A2BR in cancer. However, recent studies hav...