First report of ATP2A2 somatic mosaicism occurring during embryogenesis in transient acantholytic dermatosis

• Egile Nagusiak: Emi Hiromatsu (Egilea), Toshifumi Abe (Egilea), Kwesi Teye (Egilea), Hiroshi Koga (Egilea), Norito Ishii (Egilea), Takahiro Hamada (Egilea), Takekuni Nakama (Egilea)
• Formatua: Liburua
• Argitaratua: Wiley, 2024-09-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Abstract Transient acantholytic dermatosis (TAD) is a relatively common skin disease that typically affects older individuals, which shows clinical and histologic similarities to autosomal dominant Darier disease. TAD was recently shown to be caused by somatic ATP2A2 damaging variants. In this study...