Downregulation of an Evolutionary Young miR-1290 in an iPSC-Derived Neural Stem Cell Model of Autism Spectrum Disorder

• Main Authors: Dalia Moore (Author), Brittney M. Meays (Author), Lepakshe S. V. Madduri (Author), Farah Shahjin (Author), Subhash Chand (Author), Meng Niu (Author), Abrar Albahrani (Author), Chittibabu Guda (Author), Gurudutt Pendyala (Author), Howard S. Fox (Author), Sowmya V. Yelamanchili (Author)
• Format: Book
• Published: Hindawi Limited, 2019-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The identification of several evolutionary young miRNAs, which arose in primates, raised several possibilities for the role of such miRNAs in human-specific disease processes. We previously have identified an evolutionary young miRNA, miR-1290, to be essential in neural stem cell proliferation and n...