A Drug Repurposing Approach for Antimalarials Interfering with SARS-CoV-2 Spike Protein Receptor Binding Domain (RBD) and Human Angiotensin-Converting Enzyme 2 (ACE2)

• Auteurs principaux: Paolo Coghi (Auteur), Li Jun Yang (Auteur), Jerome P. L. Ng (Auteur), Richard K. Haynes (Auteur), Maurizio Memo (Auteur), Alessandra Gianoncelli (Auteur), Vincent Kam Wai Wong (Auteur), Giovanni Ribaudo (Auteur)
• Format: Livre
• Publié: MDPI AG, 2021-09-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Host cell invasion by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is mediated by the interaction of the viral spike protein (S) with human angiotensin-converting enzyme 2 (ACE2) through the receptor-binding domain (RBD). In this work, computational and experimental techniques were c...