MECOM Locus classical transcript isoforms affect tumor immune microenvironment and different targets in ovarian cancer

• Main Authors: Ning Lan (Author), Shuheng Bai (Author), Min Chen (Author), Xuan Wang (Author), Zhaode Feng (Author), Ying Gao (Author), Beina Hui (Author), Wen Ma (Author), Xiangxiang Zhang (Author), Fengyuan Hu (Author), Wanyi Liu (Author), Wenyang Li (Author), Fang Wu (Author), Juan Ren (Author)
• Format: Book
• Published: BMC, 2024-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract The MECOM locus is a gene frequently amplified in high-grade serous ovarian carcinoma (HGSOC). Nevertheless, the body of research examining the associations among MECOM transcripts, patient prognosis, and their role in modulating the tumor immune microenvironment (TIME) remains sparse, part...