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Renal tubule-specific Atgl deletion links kidney lipid metabolism to glucagon-like peptide 1 and insulin secretion independent of renal inflammation or lipotoxicity

Objective: Lipotoxic injury from renal lipid accumulation in obesity and type 2 diabetes (T2D) is implicated in associated kidney damage. However, models examining effects of renal ectopic lipid accumulation independent of obesity or T2D are lacking. We generated renal tubule-specific adipose trigly...

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Main Authors: Maria F. Fernandes (Author), Juan J. Aristizabal-Henao (Author), Phillip M. Marvyn (Author), Iman M'Hiri (Author), Meghan A. Wiens (Author), Monica Hoang (Author), Manuel Sebastian (Author), Renato Nachbar (Author), Philippe St-Pierre (Author), Kalsha Diaguarachchige De Silva (Author), Geoffrey A. Wood (Author), Jamie W. Joseph (Author), Christine A. Doucette (Author), André Marette (Author), Ken D. Stark (Author), Robin E. Duncan (Author)
Format: Book
Published: Elsevier, 2024-03-01T00:00:00Z.
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