Upregulation of ALOX12−12-HETE pathway impairs AMPK-dependent modulation of vascular metabolism in ApoE/LDLR−/− mice

Mitochondrial dysfunction and 12-lipoxygenase (ALOX12)-derived 12(S)-HETE production have been associated with vascular inflammation and the pathogenesis of atherosclerosis. However, the role of ALOX12 in regulating vascular energy metabolism in vascular inflammation has not been studied to date. Us...

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Main Authors: Mariola Olkowicz (Author), Agnieszka Karas (Author), Piotr Berkowicz (Author), Patrycja Kaczara (Author), Agnieszka Jasztal (Author), Zuzanna Kurylowicz (Author), Filip Fedak (Author), Hernando Rosales-Solano (Author), Kanchan Sinha Roy (Author), Agnieszka Kij (Author), Elzbieta Buczek (Author), Janusz Pawliszyn (Author), Stefan Chlopicki (Author)
Format: Book
Published: Elsevier, 2024-12-01T00:00:00Z.
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