Lp25 membrane protein from pathogenic Leptospira spp. is associated with rhabdomyolysis and oliguric acute kidney injury in a guinea pig model of leptospirosis.

• Main Authors: Patrícia A E Abreu (Author), Antonio C Seguro (Author), Daniele Canale (Author), Ana Maria G da Silva (Author), Larissa do R B Matos (Author), Tatiane B Gotti (Author), Denize Monaris (Author), Denise A de Jesus (Author), Sílvio A Vasconcellos (Author), Thales de Brito (Author), Antonio J B Magaldi (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2017-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Acute kidney injury (AKI) from leptospirosis is frequently nonoliguric with hypo- or normokalemia. Higher serum potassium levels are observed in non-survivor patients and may have been caused by more severe AKI, metabolic disarrangement, or rhabdomyolysis. An association between the creatine phospho...