Tacrolimus, a calcineurin inhibitor, promotes capsaicin-induced colonic pain in mice

TRPV1 is phosphorylated and functionally upregulated by protein kinases, and negatively regulated by phosphatases including calcineurin. Since the clinical use of calcineurin-inhibiting immunosuppressants is commonly associated with chronic diarrhea, we examined if tacrolimus, a calcineurin inhibito...

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Main Authors: Kazuki Matsui (Author), Yuka Terada (Author), Maho Tsubota (Author), Fumiko Sekiguchi (Author), Atsufumi Kawabata (Author)
Format: Book
Published: Elsevier, 2020-05-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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