Glucose Uptake in Rat Skeletal Muscle L6 Cells Is Increased by Low-Intensity Electrical Current Through the Activation of the Phosphatidylinositol-3-OH Kinase (PI-3K) / Akt Pathway

• Главные авторы: Shuichiro Yano (Автор), Saori Morino-Koga (Автор), Tatsuya Kondo (Автор), Mary Ann Suico (Автор), Tomoaki Koga (Автор), Yuichiro Shimauchi (Автор), Shingo Matsuyama (Автор), Tsuyoshi Shuto (Автор), Takashi Sato (Автор), Eiichi Araki (Автор), Hirofumi Kai (Автор)
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• Опубликовано: Elsevier, 2011-01-01T00:00:00Z.
• Предметы: article
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Activation of Akt by insulin is transmitted via phosphatidylinositol-3-OH kinase (PI-3K) and enhances glucose uptake. The PI-3K/Akt signaling is diminished in insulin resistance. Thus, approaches that activate PI-3K/Akt signaling leading to improved glucose uptake may ameliorate hyperglycemia. Here...