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Glucose Uptake in Rat Skeletal Muscle L6 Cells Is Increased by Low-Intensity Electrical Current Through the Activation of the Phosphatidylinositol-3-OH Kinase (PI-3K) / Akt Pathway

Activation of Akt by insulin is transmitted via phosphatidylinositol-3-OH kinase (PI-3K) and enhances glucose uptake. The PI-3K/Akt signaling is diminished in insulin resistance. Thus, approaches that activate PI-3K/Akt signaling leading to improved glucose uptake may ameliorate hyperglycemia. Here...

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Main Authors: Shuichiro Yano (Author), Saori Morino-Koga (Author), Tatsuya Kondo (Author), Mary Ann Suico (Author), Tomoaki Koga (Author), Yuichiro Shimauchi (Author), Shingo Matsuyama (Author), Tsuyoshi Shuto (Author), Takashi Sato (Author), Eiichi Araki (Author), Hirofumi Kai (Author)
Format: Book
Published: Elsevier, 2011-01-01T00:00:00Z.
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