Polycaprolactone - Vitamin E TPGS micelles for delivery of paclitaxel: In vitro and in vivo evaluation

• Main Authors: Ziyad Binkhathlan (Author), Osman Yusuf (Author), Raisuddin Ali (Author), Abdullah H. Alomrani (Author), Aws Alshamsan (Author), Abdullah K. Alshememry (Author), Aliyah Almomen (Author), Musaed Alkholief (Author), Ibrahim A. Aljuffali (Author), Faleh Alqahtani (Author), Saad Alobid (Author), Essam A. Ali (Author), Afsaneh Lavasanifar (Author)
• Format: Book
• Published: Elsevier, 2024-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

This study aimed to present findings on a paclitaxel (PTX)-loaded polymeric micellar formulation based on polycaprolactone-vitamin E TPGS (PCL-TPGS) and evaluate its in vitro anticancer activity as well as its in vivo pharmacokinetic profile in healthy mice in comparison to a marketed formulation. M...