Homogenous and Microbeam X-Ray Radiation Induces Proteomic Changes in the Brains of Irradiated Rats and in the Brains of Nonirradiated Cage Mate Rats

• Main Authors: Richard Smith (Author), Jiaxi Wang (Author), Colin Seymour (Author), Cristian Fernandez-Palomo (Author), Jennifer Fazzari (Author), Elisabeth Schültke (Author), Elke Bräuer-Krisch (Author), Jean Laissue (Author), Christian Schroll (Author), Carmel Mothersill (Author)
• Format: Book
• Published: SAGE Publishing, 2018-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

To evaluate microbeam radiation therapy (MRT), for brain tumor treatment, the bystander effect in nonirradiated companion animals was investigated. Adult rats were irradiated with 35 or 350 Gy at the European Synchrotron Research Facility using homogenous irradiation (HR) or MRT to the right brain h...