Directly observed treatment, short-course strategy and multidrug-resistant tuberculosis: are any modifications required?
Multidrug-resistant tuberculosis (MDRTB) should be defined as tuberculosis with resistance to at least isoniazid and rifampicin because these drugs are the cornerstone of short-course chemotherapy, and combined isoniazid and rifampicin resistance requires prolonged treatment with second-line agents....
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The World Health Organization.
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