Predicting 1-Hour Thrombolysis Effect of r-tPA in Patients With Acute Ischemic Stroke Using Machine Learning Algorithm

• Main Authors: Bin Zhu (Author), Jianlei Zhao (Author), Mingnan Cao (Author), Wanliang Du (Author), Liuqing Yang (Author), Mingliang Su (Author), Yue Tian (Author), Mingfen Wu (Author), Tingxi Wu (Author), Manxia Wang (Author), Xingquan Zhao (Author), Zhigang Zhao (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Thrombolysis with r-tPA is recommended for patients after acute ischemic stroke (AIS) within 4.5 h of symptom onset. However, only a few patients benefit from this therapeutic regimen. Thus, we aimed to develop an interpretable machine learning (ML)-based model to predict the thrombolysi...