Mu-Opioid Receptor Agonist Induces Kir3 Currents in Mouse Peripheral Sensory Neurons - Effects of Nerve Injury

• Autors principals: Philip Stötzner (Autor), Viola Spahn (Autor), Melih Ö. Celik (Autor), Dominika Labuz (Autor), Halina Machelska (Autor)
• Format: Llibre
• Publicat: Frontiers Media S.A., 2018-12-01T00:00:00Z.
• Matèries: article
• Accés en línia: Connect to this object online.

Neuropathic pain often arises from damage to peripheral nerves and is difficult to treat. Activation of opioid receptors in peripheral sensory neurons is devoid of respiratory depression, sedation, nausea, and addiction mediated in the brain, and ameliorates neuropathic pain in animal models. Mechan...