Temporal and spatial heterogeneity of HER2 status in metastatic colorectal cancer

• Main Authors: Flavia D'Angelo (Author), Franck Monnien (Author), Alexis Overs (Author), Irvin Pem (Author), Fanny Dor (Author), Marine Abad (Author), Sophie Felix (Author), Zohair Selmani (Author), Zaher Lakkis (Author), Christophe Borg (Author), Alexandre Doussot (Author), Fréderic Bibeau (Author), Chloé Molimard (Author)
• Format: Book
• Published: BMC, 2024-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background HER2-targeted therapies have recently emerged as an option in the management of metastatic colorectal cancer (mCRC) overexpressing HER2. However, data regarding HER2 status in primary CRC and its corresponding liver metastases are limited, potentially influencing clinical decisio...