Transient Receptor Potential Vanilloid 1 - a Polymodal Nociceptive Receptor - Plays a Crucial Role in Formaldehyde-Induced Skin Inflammation in Mice

• Main Authors: Haruki Usuda (Author), Takumi Endo (Author), Ayumi Shimouchi (Author), Asaka Saito (Author), Makoto Tominaga (Author), Hirotaka Yamashita (Author), Hiroichi Nagai (Author), Naoki Inagaki (Author), Hiroyuki Tanaka (Author)
• Format: Book
• Published: Elsevier, 2012-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Formaldehyde (FA) is irritating to the skin and is the main cause of sick building syndrome. However, the cutaneous reaction induced by long-term FA exposure has not been fully investigated. In our previous study, we demonstrated that repeated painting of 2% - 10% FA on mouse ears caused marked ear...