A Phase I, Randomized, Single-Dose Study to Evaluate the Biosimilarity of QL1206 to Denosumab Among Chinese Healthy Subjects

• Main Authors: Hong Zhang (Author), Min Wu (Author), Xiaoxue Zhu (Author), Cuiyun Li (Author), Xiaojiao Li (Author), Jixuan Sun (Author), Chengjiao Liu (Author), Quan Liu (Author), Wei Wei (Author), Junqi Niu (Author), Yanhua Ding (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

ObjectiveThis study was conducted to explore the tolerance, variability, pharmacokinetics (PK), and pharmacodynamics (PD) of denosumab biosimilar (QL1206) in healthy Chinese subjects.MethodsThis is a randomized, double-blind, two-arm, parallel study performed to examine the bioequivalence of denosum...