IL-21/IL-21R Regulates the Neutrophil-Mediated Pathologic Immune Response during Chlamydial Respiratory Infection

• Main Authors: Jiajia Zeng (Author), Yueyue Xu (Author), Lu Tan (Author), Xiaoyu Zha (Author), Shuaini Yang (Author), Hong Zhang (Author), Yuqing Tuo (Author), Ruoyuan Sun (Author), Wenhao Niu (Author), Gaoju Pang (Author), Lida Sun (Author), Hong Bai (Author)
• Format: Book
• Published: Hindawi Limited, 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

IL-21/IL-21R was documented to participate in the regulation of multiple infection and inflammation. During Chlamydia muridarum (C. muridarum) respiratory infection, our previous study had revealed that the absence of this signal induced enhanced resistance to infection with higher protective Th1/Th...