Cyp2c-deficiency depletes muricholic acids and protects against high-fat diet-induced obesity in male mice but promotes liver damage

Objective: Murine-specific muricholic acids (MCAs) are reported to protect against obesity and associated metabolic disorders. However, the response of mice with genetic depletion of MCA to an obesogenic diet has not been evaluated. We used Cyp2c-deficient (Cyp2c−/−) mice, which lack MCAs and thus h...

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Main Authors: Antwi-Boasiako Oteng (Author), Sei Higuchi (Author), Alexander S. Banks (Author), Rebecca A. Haeusler (Author)
Format: Book
Published: Elsevier, 2021-11-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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