Irisin Protects Against Motor Dysfunction of Rats with Spinal Cord Injury via Adenosine 5'-Monophosphate (AMP)-Activated Protein Kinase-Nuclear Factor Kappa-B Pathway

• Main Authors: Xi Jiang (Author), Zhihong Shen (Author), Jin Chen (Author), Chao Wang (Author), Zhan Gao (Author), Songling Yu (Author), Xuefeng Yu (Author), Lei Chen (Author), Lexing Xu (Author), Ziwei Chen (Author), Wenjuan Ni (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The aim of the present research was to investigate the effects of irisin, a skeletal muscle-derived myokine, on spinal cord injury (SCI) in rats and explore the possible mechanisms. SCI model was constructed in male SD rats. The effects of irisin on SCI rats were assessed via behavior tests includin...