Quercetin mitigates rheumatoid arthritis by inhibiting adenosine deaminase in rats

• Main Authors: Karim Samy El-Said (Author), Amira Atta (Author), Maysa A. Mobasher (Author), Mousa O. Germoush (Author), Tarek M. Mohamed (Author), Maha M. Salem (Author)
• Format: Bog
• Udgivet: BMC, 2022-02-01T00:00:00Z.
• Fag: article
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Abstract Rheumatoid arthritis (RA) is a chronic inflammatory joint disease characterized by synovial proliferation and bone destruction. Adenosine deaminase (ADA) is a key inflammatory enzyme that increases joint stiffness and pain in RA. In this study, we evaluated the in-silico, and in vivo inhibi...