Protein Tyrosine Phosphatase SHP-2 Is Positively Involved in Platelet-Derived Growth Factor-Signaling in Vascular Neointima Formation via the Reactive Oxygen Species-Related Pathway

• Main Authors: Kyung-Jong Won (Author), Hwan Myung Lee (Author), Chang-Kwon Lee (Author), Hai Yue Lin (Author), Haerang Na (Author), Ki Won Lim (Author), Hui Yul Roh (Author), Seobo Sim (Author), Hyuk Song (Author), Wahn Soo Choi (Author), Seung Hyun Lee (Author), Bokyung Kim (Author)
• Format: Book
• Published: Elsevier, 2011-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The roles of Src homology domain 2-containing protein tyrosine phosphatase 2 (SHP-2) and its signaling in atherosclerosis have not been explored. Therefore, we investigated the roles of SHP-2 in the movement of rat aortic smooth muscle cells (RASMCs) and in the neointima formation of the carotid art...