Novel variants in the ACTA2 and MYH11 genes in a Cypriot family with thoracic aortic aneurysms: a case report

• Auteurs principaux: Anna Keravnou (Auteur), Evy Bashiardes (Auteur), Kyriaki Michailidou (Auteur), Marinos Soteriou (Auteur), Areti Moushi (Auteur), Marios Cariolou (Auteur)
• Format: Livre
• Publié: BMC, 2018-12-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Abstract Background Thoracic aortic aneurysm (TAA) and/or thoracic aortic aneurysm and dissection (TAAD) is characterized by a considerable risk of morbidity and mortality of affected individuals. It is inherited in an autosomal dominant pattern and the 20% of patients with non-syndromic TAA have a...