Inhibitory Effect of Zacopride on Cisplatin-Induced Delayed Emesis in Ferrets

• Hoofdauteurs: Yamakuni Hisashi (Auteur), Nakayama Hiroe (Auteur), Matsui Shigeo (Auteur), Imazumi Katsunori (Auteur), Matsuo Masahiko (Auteur), Mutoh Seitaro (Auteur)
• Formaat: Boek
• Gepubliceerd in: Elsevier, 2006-01-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Abstract.: We evaluated the antiemetic effect of zacopride, a potent 5-HT3-receptor antagonist with 5-HT4-receptor agonist properties, on delayed emesis caused by cisplatin (5 mg/kg, i.p.) in ferrets, compared with granisetron, a selective 5-HT3-receptor antagonist. Multiple intravenous injections o...