Pharmacokinetic Principles and Their Application to Central Nervous System Tumors

• Autori principali: Joelle P. Straehla (Autore), Katherine E. Warren (Autore)
• Natura: Libro
• Pubblicazione: MDPI AG, 2020-10-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Despite increasing knowledge of the biologic drivers of central nervous system tumors, most targeted agents trialed to date have not shown activity against these tumors in clinical trials. To effectively treat central nervous system tumors, an active drug must achieve and maintain an effective expos...