Specific gene module pair-based target identification and drug discovery

• Main Authors: Peng Li (Author), Chujie Bai (Author), Lingmin Zhan (Author), Haoran Zhang (Author), Yuanyuan Zhang (Author), Wuxia Zhang (Author), Yingdong Wang (Author), Jinzhong Zhao (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Identification of the biological targets of a compound is of paramount importance for the exploration of the mechanism of action of drugs and for the development of novel drugs. A concept of the Connectivity Map (CMap) was previously proposed to connect genes, drugs, and disease states based on the...