A novel lipid prodrug strategy for sustained delivery of hexadecyloxypropyl 9-[2-(phosphonomethoxy)ethyl]guanine (HDP-PMEG) on unwanted ocular proliferation

• Asıl Yazarlar: Mei Chen (Yazar), Jiangping Hou (Yazar), Guilin Tan (Yazar), Peng Xie (Yazar), William R. Freeman (Yazar), James R. Beadle (Yazar), Karl Y. Hostetler (Yazar), Lingyun Cheng (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Taylor & Francis Group, 2017-01-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Proliferative vitreoretinopathy (PVR) is a blinding eye disease and there is no effective pharmacological measure to prevent PVR development. The difficulty comes from lack of potent antiproliferative agent and lack of sustained delivery to cover high-risk time window for PVR to develop. Lipid prodr...