Development of a Drosophila melanogaster spliceosensor system for in vivo high-throughput screening in myotonic dystrophy type 1

Development of a Drosophila melanogaster spliceosensor system for in vivo high-throughput screening in myotonic dystrophy type 1

Alternative splicing of pre-mRNAs is an important mechanism that regulates cellular function in higher eukaryotes. A growing number of human genetic diseases involve splicing defects that are directly connected to their pathology. In myotonic dystrophy type 1 (DM1), several clinical manifestations h...

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Main Authors: Irma García-Alcover (Author), Jordi Colonques-Bellmunt (Author), Raquel Garijo (Author), José R. Tormo (Author), Rubén Artero (Author), Mari Carmen Álvarez-Abril (Author), Arturo López Castel (Author), Manuel Pérez-Alonso (Author)
Format: Book
Published: The Company of Biologists, 2014-11-01T00:00:00Z.
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3rd Floor Main Library

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