Delivery of Functional Anti-miR-9 by Mesenchymal Stem Cell-derived Exosomes to Glioblastoma Multiforme Cells Conferred Chemosensitivity

Delivery of Functional Anti-miR-9 by Mesenchymal Stem Cell-derived Exosomes to Glioblastoma Multiforme Cells Conferred Chemosensitivity

Glioblastoma multiforme (GBM), the most common and lethal tumor of the adult brain, generally shows chemo- and radioresistance. MicroRNAs (miRs) regulate physiological processes, such as resistance of GBM cells to temozolomide (TMZ). Although miRs are attractive targets for cancer therapeutics, the...

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Main Authors: Jessian L Munoz (Author), Sarah A Bliss (Author), Steven J Greco (Author), Shakti H Ramkissoon (Author), Keith L Ligon (Author), Pranela Rameshwar (Author)
Format: Book
Published: Elsevier, 2013-01-01T00:00:00Z.
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3rd Floor Main Library

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