Comparison of tumor and two types of paratumoral tissues highlighted epigenetic regulation of transcription during field cancerization in non-small cell lung cancer

• Main Authors: Qiushi Wang (Author), Libo Wu (Author), Jiaxing Yu (Author), Guanghua Li (Author), Pengfei Zhang (Author), Haozhe Wang (Author), Lin Shao (Author), Jinying Liu (Author), Weixi Shen (Author)
• Format: Book
• Published: BMC, 2022-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Field cancerization is the process in which a population of normal or pre-malignant cells is affected by oncogenic alterations leading to progressive molecular changes that drive malignant transformation. Aberrant DNA methylation has been implicated in early cancer development in...