Carnosine Alleviates Knee Osteoarthritis and Promotes Synoviocyte Protection via Activating the Nrf2/HO-1 Signaling Pathway: An In-Vivo and In-Vitro Study

• Auteurs principaux: Prabhakar Busa (Auteur), Sing-Ong Lee (Auteur), Niancih Huang (Auteur), Yaswanth Kuthati (Auteur), Chih-Shung Wong (Auteur)
• Format: Livre
• Publié: MDPI AG, 2022-06-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

The most common joint disease in the elderly is knee osteoarthritis (OA). It is distinguished by cartilage degradation, subchondral bone loss, and a decrease in joint space. We studied the effects of carnosine (CA) on knee OA in male Wistar rats. OA is induced by anterior cruciate ligament transecti...