Homo-PROTAC mediated suicide of MDM2 to treat non-small cell lung cancer
The dose-related adverse effects of MDM2‒P53 inhibitors have caused significant concern in the development of clinical safe anticancer agents. Herein we report an unprecedented homo-PROTAC strategy for more effective disruption of MDM2‒P53 interaction. The design concept is inspired by the capacity...
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Main Authors: | , , , , , , , |
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Format: | Book |
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Elsevier,
2021-06-01T00:00:00Z.
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Internet
Connect to this object online.3rd Floor Main Library
Call Number: |
A1234.567 |
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Copy 1 | Available |