Haloperidol affects coupling between QT and RR intervals in guinea pig isolated heart

• Main Authors: Petr Vesely (Author), Tibor Stracina (Author), Miroslava Hlavacova (Author), Josef Halamek (Author), Jana Kolarova (Author), Veronika Olejnickova (Author), Veronika Mrkvicova (Author), Hana Paulova (Author), Marie Novakova (Author)
• Format: Book
• Published: Elsevier, 2019-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Prolonged QT interval is an independent risk factor for development of ventricular arrhythmias. Haloperidol is one of the drugs inducing QT prolongation. Previous studies showed that haloperidol affects not only QT duration but also heart rate (RR interval). The present work focused on relationship...