The Impact of Acetyl-CoA and Aspartate Shortages on the <i>N</i>-Acetylaspartate Level in Different Models of Cholinergic Neurons
<i>N</i>-acetylaspartate is produced by neuronal aspartate N-acetyltransferase (NAT8L) from acetyl-CoA and aspartate. In cholinergic neurons, acetyl-CoA is also utilized in the mitochondrial tricarboxylic acid cycle and in acetylcholine production pathways. While aspartate has to be shar...
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| Main Authors: | , , , , , |
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| Format: | Book |
| Published: |
MDPI AG,
2020-06-01T00:00:00Z.
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