Association of IL18 gene polymorphisms (positions -656 G/T, -137 G/C and +105A/C) with Kala-Azar

• Prif Awduron: Yaser Mansoori (Awdur), Ali Moravej (Awdur), Sohrab Najafipour (Awdur), Seyed Amin Kouhpayeh (Awdur), Mohammad Hasan Meshkibaf (Awdur), Abbas Abdollahi (Awdur), Manochehr Rasouli (Awdur), Ghader Allahverdi (Awdur)
• Fformat: Llyfr
• Cyhoeddwyd: Fasa University of Medical Sciences, 2012-08-01T00:00:00Z.
• Pynciau: article
• Mynediad Ar-lein: Connect to this object online.

Background & Objective: Host resistance to Leishmania infection is mediated by cellular immune responses leading to macrophage activation and parasite killing. IL-18 known as interferon-γ inducing factor, stimulate IFN-γ production by T-cells. According to the important role of IL-18 in defense...