Case Report: Tuberous sclerosis complex-associated hemihypertrophy successfully treated with mTOR inhibitor sirolimus

• Main Authors: Konomi Shimoda (Author), Hiroyuki Iwasaki (Author), Yoko Mizuno (Author), Masafumi Seki (Author), Masakazu Mimaki (Author), Motohiro Kato (Author), Aya Shinozaki-Ushiku (Author), Harushi Mori (Author), Seishi Ogawa (Author), Masashi Mizuguchi (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Tuberous sclerosis complex (TSC) is an autosomal dominant disorder caused by a mutation in either of the two tumor suppressor genes, TSC1 and TSC2. Due to dysregulated activity of the mammalian target of rapamycin (mTOR) pathway, hamartomas or benign tumors frequently occur in many organs and are of...