Population Pharmacokinetics and Dosing Regimen Optimization of Latamoxef in Chinese Children

• Main Authors: Yang Wang (Author), Dan Sun (Author), Yan Mei (Author), Sanlan Wu (Author), Xinlin Li (Author), Sichan Li (Author), Jun Wang (Author), Liuliu Gao (Author), Hua Xu (Author), Yali Tuo (Author)
• Format: Book
• Published: MDPI AG, 2022-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The present study aimed to establish population pharmacokinetic models of latamoxef, as well as its R- and S-epimers, and generate findings to guide the individualized administration of latamoxef in pediatric patients. A total of 145 in-hospital children aged 0.08-10.58 years old were included in th...