KMT2A/C mutations function as a potential predictive biomarker for immunotherapy in solid tumors

• 主要な著者: Rui Zhang (著者), Hao-Xiang Wu (著者), Ming Xu (著者), Xiaoyan Xie (著者)
• フォーマット: 図書
• 出版事項: BMC, 2020-12-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Abstract Epigenetic factors play important roles in tumor immunology. Histone-lysine N-methyltransferase 2 (KMT2) family genes exert histone H3 methylation, but its role in immunotherapy remains unclear. Our study is the first to investigate the correlation between KMT2 gene mutations and the clinic...