Emerging Three-Dimensional Hepatic Models in Relation to Traditional Two-Dimensional In Vitro Assays for Evaluating Drug Metabolism and Hepatoxicity
A vital aspect of preclinical drug development involves assessing hepatic metabolism and toxicity. These screenings are typically conducted utilizing in vitro assays and in vivo animal models; however, recent advancements in tissue engineering offer a hybrid approach to augment current protocols. Th...
Saved in:
Main Authors: | Erin Milner (Author), Michael Ainsworth (Author), Matthew McDonough (Author), Benjamin Stevens (Author), Johannah Buehrer (Author), Richard Delzell (Author), Cameron Wilson (Author), Jason Barnhill (Author) |
---|---|
Format: | Book |
Published: |
Elsevier,
2020-12-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Obeticholic Acid Induces Hepatoxicity Via FXR in the NAFLD Mice
by: Chuangzhen Lin, et al.
Published: (2022) -
Dimensiones profundas
by: Dalia Valderrama Tapia
Published: (2022) -
DDAH1 Protects against Acetaminophen-Induced Liver Hepatoxicity in Mice
by: Xiyue Shen, et al.
Published: (2022) -
CHOP Regulates Endoplasmic Reticulum Stress-Mediated Hepatoxicity Induced by Monocrotaline
by: Yazhou Guo, et al.
Published: (2021) -
Antioxidative effect of metformin on valproic acid induced hepatoxicity in male rats
by: Intesar Tarik Numan, et al.
Published: (2022)