Stat3 Tyrosine 705 and Serine 727 Phosphorylation Associate With Clinicopathological Characteristics and Distinct Tumor Cell Phenotypes in Triple-Negative Breast Cancer

• Autori principali: Michaela Stenckova (Autore), Rudolf Nenutil (Autore), Borivoj Vojtesek (Autore), Philip J. Coates (Autore)
• Natura: Libro
• Pubblicazione: Frontiers Media S.A., 2022-08-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Signal transducer and activator of transcription 3 (Stat3) is responsible for many aspects of normal development and contributes to the development and progression of cancer through regulating epithelial cell identity and cancer stem cells. In breast cancer, Stat3 is associated with triple-negative...