Development of a Compartmental Pharmacokinetic Model for Molecular Radiotherapy with ¹³¹I-CLR1404

• Main Authors: Sara Neira (Author), Araceli Gago-Arias (Author), Isabel Gónzalez-Crespo (Author), Jacobo Guiu-Souto (Author), Juan Pardo-Montero (Author)
• Format: Book
• Published: MDPI AG, 2021-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Pharmacokinetic modeling of the radiopharmaceuticals used in molecular radiotherapy is an important step towards accurate radiation dosimetry of such therapies. In this paper, we present a pharmacokinetic model for CLR1404, a phospholipid ether analog that, labeled with ¹²⁴I/&...